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目的:分析预防性补钙对预测妊娠期高血压疾病(PIH)阳性孕妇的效果。方法:选取2010年1月-2012年12月我院妇产科预测为PIH阳性并血清钙偏低的孕妇(≥妊娠20周)476例,按入院顺序随机分为两组各238例,治疗组予口服复方氨基酸螯合钙胶囊1g,每日2次,直至分娩;对照组未服钙剂。比较两组孕妇PIH及胎儿受限(FGR)的发生率。结果:治疗组孕妇补钙后的血钙值较补钙前明显增高(P<0.05),对照组无明显变化(P>0.05)。两组比较,P<0.05;治疗组孕妇PIH、FGR的发生率(7.56%、5.46%)均明显低于对照组(23.53%、17.23%),两组比较,P均<0.05。结论:对PIH阳性孕妇预防性补钙,可降低PIH及FGR的发生率。孕妇定期产前检查,综合评估其血钙状况,是防治PIH、改善胎儿预后的重要步骤。
Objective: To analyze the effect of prophylactic calcium supplement on pregnant women with gestational hypertension (PIH). Methods: From January 2010 to December 2012, 476 pregnant women (≥20 gestational weeks) pregnant women with obstetrics and gynecology who were positive for PIH and low serum calcium were enrolled in this study. They were randomly divided into 238 cases Group oral compound amino acid chelated calcium capsules 1g, 2 times a day until delivery; control group was not served calcium. The incidence of PIH and fetal restriction (FGR) in both groups were compared. Results: The blood calcium level of pregnant women after treatment with calcium was significantly higher than that before calcium supplementation (P <0.05), but there was no significant change in the control group (P> 0.05). The incidence of PIH and FGR in the treatment group was significantly lower than that in the control group (7.56%, 5.46%, 23.53%, 17.23%, P <0.05). Conclusion: Preventive calcium supplementation for PIH-positive pregnant women can reduce the incidence of PIH and FGR. Regular prenatal examination of pregnant women, a comprehensive assessment of the status of serum calcium, PIH prevention and treatment to improve fetal prognosis an important step.