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目的 :以布洛芬替代氨基比林配制小儿退热合剂 ,并制订质量控制方法。考察退热合剂的降温情况及临床应用效果。方法 :通过控制温度和时间的方法确保水合氯醛的回收率。并通过临床应用证实制剂的退热效果。结果 :小儿退热合剂质量稳定 ,退热效果好。结论 :小儿退热合剂可以替代原合剂在医院配制使用
OBJECTIVE: To prepare the antipyretic compound for children with ibuprofen instead of aminopyrine and to develop a quality control method. Investigate the cooling effect of compound antipyretic and clinical effect. Method: The recovery of chloral hydrate was ensured by controlling the temperature and time. And through clinical application to confirm the preparation of the antipyretic effect. Results: Pediatric antipyretic mixture quality and antipyretic effect is good. Conclusion: Pediatric antipyretic mixture can replace the original mixture in the hospital preparation