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计算机分子模拟方法研究了２－（４－氨酰基－２－噻唑基）－１，４－脱水－Ｌ－木糖醇及其氟代衍生物的糖基构象．计算结果显示，６个碳核苷类似物的糖基构象均为Ｓ型．核磁共振谱和晶体Ｘ射线衍射结果与计算结果相吻合．
The molecular conformation of 2- (4-aminoacyl-2-thiazolyl) -1,4-anhydro-L-xylitol and its fluorinated derivatives was investigated by computer molecular modeling method. The calculated results show that the glycosyl conformations of all six carbon nucleoside analogues are S type. Nuclear magnetic resonance spectrum and crystal X-ray diffraction results are consistent with the calculated results.