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目的:探究欣普贝生用于妊娠晚期促宫颈成熟及引产的临床效果。方法:选取选取2010年10月至2012年10月在我院分娩的初产妇120例,采用随机的方法将其分为对照组和观察组,每组60例。对照组采用缩宫素(Oxytocinum)进行治疗,观察组采用欣普贝生进行治疗,观察比较两组的分娩结局及产程。结果:对照组用药到临产时间、总产程以及第一产程时间均明显长于观察组,差异具有统计学意义(P<0.05)。对照组60例中,24内临产率为38.33%,剖宫产率26.66%;观察组60例中,24h内临产50例,第二天配合缩宫素引产成功临产5例,由于引产失败而改行剖宫产5例。24内临产率为83.33%,剖宫产率8.33%。两组24h内临产率,剖宫产率差异具有统计学意义(P<0.05)。此外,两组胎儿宫内窘迫以及产后出血量方面,差异无统计学意义(P>0.05)。结论:在妊娠晚期促宫颈成熟及引产中应用欣普贝生简便、有效、安全性高,减少了引产失败后进行的剖宫产手术率,提升了阴道分娩的可能性。值得临床借鉴使用。
Objective: To investigate the clinical effect of Hinbu Beisin in promoting cervical ripening and induction of labor during the third trimester of pregnancy. Methods: A total of 120 primiparae women were delivered in our hospital from October 2010 to October 2012. They were randomly divided into control group and observation group, with 60 cases in each group. The control group was treated with Oxytocinum, and the observation group was treated with Hippocampus. The delivery and labor course were compared between the two groups. Results: The control group was significantly longer than the observation group in the duration of labor, the duration of labor, and the duration of the first stage of labor. The difference was statistically significant (P <0.05). In the control group of 60 cases, the rate of 24 was 38.33% and the rate of cesarean section was 26.66%. Among the 60 cases in the observation group, 50 cases were delivered within 24 hours and 5 cases were successfully induced with oxytocin in the next day. Due to the failure of induction of labor Cesarean section to 5 cases. 24, the internal rate of 83.33%, cesarean section rate of 8.33%. The intrapartum labor rate within 24 h, cesarean section rate difference was statistically significant (P <0.05). In addition, two groups of fetal distress and postpartum hemorrhage, the difference was not statistically significant (P> 0.05). Conclusion: It is simple, effective and safe to apply cervicin to cervical ripening and induction of labor during the third trimester of pregnancy. It can reduce the rate of cesarean section after the failure of induction of labor and improve the possibility of vaginal delivery. It is worth to use for clinical reference.