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目的探讨缺血修饰白蛋白(ischemia modified albumin,IMA)对老年急性冠脉综合征的早期诊断价值。方法入选的为胸痛发作4h内急诊的老年患者,通过白蛋白钴结合试验(ACB法)、免疫组化法分别检测患者的血清IMA、肌钙蛋白T(cTnT)及心电图,并与健康对照组进行比较,评价IMA对老年急性冠脉综合征的早期诊断价值。结果血清IMA、cTnT、ECG诊断急性冠脉综合征的敏感性分别为84.3%、31.8%、45.6%。结论 IMA可明显提高老年急性冠脉综合征早期诊断的敏感性。
Objective To investigate the value of ischemia modified albumin (IMA) in early diagnosis of senile acute coronary syndrome. Methods Elderly patients with acute chest pain within 4 hours were enrolled in this study. Serum IMA, cTnT and electrocardiogram were detected by ACB method and immunohistochemistry. To evaluate the value of IMA in early diagnosis of senile acute coronary syndrome. Results The sensitivity of serum IMA, cTnT and ECG in diagnosing acute coronary syndrome were 84.3%, 31.8% and 45.6% respectively. Conclusion IMA can significantly improve the early diagnosis of acute coronary syndrome in elderly patients.