患者女,15岁,学生。因反复大关节疼痛伴双踝关节肿胀、低热1年,于1989年1月9日入院。患者1年前超病,曾经多家医院诊为“风湿性关节炎”进行治疗后病情好转,但以后经常出现大关节游走性疼痛,踝关节肿胀。检查:下肢小腿伸侧和踝关节附近有皮下小结和结节性红斑。双踝关节肿胀,压痛.实验室检查:白细胞8.4×10~9/L,红细胞33×10~(18)/L, Female patient, 15 years old, student. Due to repeated large joint pain with double ankle swelling, fever 1 year, on January 9, 1989 admission. One year ago, the patient was super-superficially. After having been diagnosed as “rheumatoid arthritis” in several hospitals, his condition improved. However, he often had swollen and painful large joint swollen joints and ankle swelling. Check: Lower extremity leg extensor and ankle near the subcutaneous nodules and erythema. Ankle joint swelling, tenderness. Laboratory tests: white blood cells 8.4 × 10 ~ 9 / L, red blood cells 33 × 10 ~ (18) / L,