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目的:比较巴曲亭的三种不同用法在经尿道前列腺电切术中止血作用的差异。方法:将90例BPH患者随机分为联合用药组、全身用药组及冲洗液用药组,分别在术前及术后运用三种方法使用巴曲亭,通过比较三组患者术中、术后出血量、总出血量的多少及膀胱冲洗时间的长短来对比三种方法的止血疗效差异,并根据患者术前及术后的血凝数据来确定该药的安全性。结果:联合用药组的术中、术后出血量及总出血量均较其余两组明显减少,且并未影响患者的凝血状态。结论:联合运用巴曲亭能明显减少经尿道前列腺患者的手术出血,疗效肯定,使用安全,值得临床推广。
OBJECTIVE: To compare the differences of hemostatic effects among three different uses of batrikuting in transurethral resection of the prostate. Methods: Ninety patients with BPH were randomly divided into combination group, systemic administration group and irrigant solution group. Batroxobin was used by three methods before and after operation respectively. By comparing the intraoperative and postoperative blood loss , The total amount of bleeding and bladder irrigation time length to compare the three methods of hemostasis efficacy differences, and based on the patient’s preoperative and postoperative blood coagulation data to determine the safety of the drug. Results: The intraoperative and postoperative bleeding volume and the total amount of bleeding in the combination group were significantly decreased compared with the other two groups, and did not affect the coagulation status of the patients. Conclusion: The combined use of Batritang can significantly reduce the surgical bleeding in patients with transurethral prostatitis, efficacy is sure, safe to use, worthy of clinical promotion.