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目的：探讨ｓＣＤ２３ 在类风湿关节炎（ＲＡ） 发病中的作用。方法：采用固相酶联免疫分析（ＥＬＩＳＡ） 法检测３６ 例ＲＡ 患者血浆ｓＣＤ２３ 含量。结果：ＲＡ 患者血浆ｓＣＤ２３ 较献血员组明显升高（ Ｐ＜ ０ ．０１） ，而关节损伤组与献血员组间无显著差异，ＲＡ 患者血浆ｓＣＤ２３ 与ＣＲＰ呈正相关（ｒ ＝０ ．４６８ ，Ｐ＜ ０ ．０１） ，但与ＥＳＲ 间无相关性。结论：ｓＣＤ２３ 可能参与ＲＡ 的发病，血浆ｓＣＤ２３ 检测有助于对ＲＡ病情发展作出判断。
Objective: To investigate the role of sCD23 in the pathogenesis of rheumatoid arthritis (RA). Methods: Plasma sCD23 levels in 36 patients with RA were detected by enzyme-linked immunosorbent assay (ELISA). Results: The plasma levels of sCD23 in patients with RA were significantly higher than those in blood donors (P <0.01), but there was no significant difference between the groups of injuries and blood donors. The levels of sCD23 in patients with RA were positively correlated with CRP (r = 0.488, P <0 .01), but no correlation with ESR. Conclusion: sCD23 may be involved in the pathogenesis of RA. The detection of plasma sCD23 is helpful to judge the progression of RA.