关于晚期癌症引起疼痛的问题已有各种报告。本文对食道、胃、肝、胰、结肠等的消化道癌及肺癌、子宫癌、白血病等疼痛发生的频度、持续时间、住院治疗等问题进行回顾性调查,并用多变量分析法进行分析。方法本组444例,均死于恶性肿瘤。男254例,女190例。平均年龄63.5岁。食道癌24例,胃癌110例,其中手术切除治愈55例(胃-1),剖腹探查术55例(胃-2);肝癌61例,胰癌39例,结肠癌49例,直肠癌37例,肺癌39例,子宫卵巢癌30例,膀胱及前列腺癌32例,白血病及恶性淋巴瘤23例。胃、结肠及直肠癌均经手术证实系原发癌,其他癌症组也经手术或尸解确诊。调查项目为癌早期有无疼痛及疼痛的程度,用(-)、(+)表示,以及各种不同程度的疼痛发生频度。疼痛(-):不需给镇痛治疗者,疼痛(+);需定时给镇痛治疗者;疼痛(++):对消炎镇痛药无效,需给拮抗性镇痛药及麻醉药每日2次以上,连用5日以上或需用神经阻滞麻醉者。疼痛持续天数是以疼痛出现 There have been various reports on the problem of pain caused by advanced cancer. This article reviews the frequency, duration, and hospitalization of gastrointestinal cancers such as esophagus, stomach, liver, pancreas, and colon, and lung cancer, uterine cancer, and leukemia, and conducts a multivariate analysis. Methods 444 cases in this group all died of malignant tumors. There were 254 males and 190 females. The average age is 63.5 years old. 24 cases of esophageal cancer and 110 cases of gastric cancer, of which 55 cases (stomach-1) were cured by surgical resection, 55 cases (stomach-2) by laparotomy, 61 cases of liver cancer, 39 cases of pancreatic cancer, 49 cases of colon cancer, and 37 cases of rectal cancer. There were 39 cases of lung cancer, 30 cases of uterine and ovarian cancer, 32 cases of bladder and prostate cancer, and 23 cases of leukemia and malignant lymphoma. Stomach, colon, and rectal cancer were confirmed by surgery as primary cancers, and other cancer groups were diagnosed with surgery or autopsy. The investigation items included the degree of pain and pain in early stage of cancer, which was indicated by (-) and (+), and the frequency of various degrees of pain. Pain (-): No need for analgesia, Pain (+); Timely analgesia for treatment; Pain (++): Ineffective for anti-inflammatory analgesics, Antagonist and anesthetic Day 2 or more, use more than 5 days or need to use nerve block anesthesia. The number of pain days is the number of pain