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目的分析晚期非小细胞肺癌采用深部热疗联合化疗治疗的临床疗效。方法选取医院收治的晚期非小细胞肺癌患者56例为研究对象,根据治疗方法不同分为观察组和对照组,每组28例。对照组单独化疗,观察组在对照组治疗的基础上联合深部热疗。比较2组患者临床症状改善情况及不良反应。结果观察组治疗总有效率为82.14%,高于对照组的57.14%,差异有统计学意义(P<0.05)。对照组6个月内死亡15例,生存率为46.43%;观察组6个月内死亡7例,生存率为75.00%。2组患者不良反应发生率比较差异无统计学意义(P>0.05)。结论深部热疗联合化疗治疗能有效改善晚期非小细胞肺癌患者临床症状,抑制癌细胞发展和扩散,提高患者生存质量,延长生存时间,稳定性和安全性良好,能有效控制患者病情。
Objective To analyze the clinical effect of deep hyperthermia combined with chemotherapy in advanced non-small cell lung cancer. Methods Fifty-six patients with advanced non-small cell lung cancer admitted to hospital were enrolled in this study. According to the different treatment methods, they were divided into observation group and control group, 28 cases in each group. The control group chemotherapy alone, the observation group in the control group based on the combination of deep hyperthermia. The clinical symptoms and adverse reactions in two groups were compared. Results The total effective rate of observation group was 82.14%, which was higher than that of control group (57.14%), the difference was statistically significant (P <0.05). In the control group, 15 patients died within 6 months and the survival rate was 46.43%. In the observation group, 7 patients died within 6 months and the survival rate was 75.00%. There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion Deep hyperthermia combined with chemotherapy can effectively improve the clinical symptoms, inhibit the development and spread of cancer cells, improve the quality of life, prolong the survival time, improve the stability and safety of patients with advanced non-small cell lung cancer, and can effectively control the patient’s condition.