烟草内的有毒成分有20多种,其中最引人瞩目的是一氧化碳(CO)和菸碱(即尼古丁)。Stedman 氏曾对1000余名吸烟者进行调查,证实它对心血管、呼吸和免疫系统以及凝血机制、药物代谢、精神状态都有不同程度的影响。因此,了解吸烟、戒烟对机体的作用,对于提高围术期的安全性是有裨益的。一、心血管系统1.CO 的作用:吸烟时,入口的CO 浓度为1～5%,经口咽腔稀释后降至400ppm。由于CO 与血红蛋白(Hb)的亲合力比氧大 More than 20 kinds of toxic components in tobacco, the most notable ones are carbon monoxide (CO) and nicotine (ie nicotine). Stedman’s survey of more than 1,000 smokers confirmed that it affects cardiovascular, respiratory and immune systems as well as coagulation mechanisms, drug metabolism, and mental status to varying degrees. Therefore, to understand smoking, smoking cessation on the body’s role in improving perioperative safety is beneficial. First, the cardiovascular system 1.CO role: smoking, the entrance of CO concentration of 1 to 5%, after oral oropharyngeal dilution to 400ppm. Because CO and hemoglobin (Hb) affinity than oxygen