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盐酸他喷他朵是一种新型的具有双重功效的中枢止痛剂,它既是μ型阿片受体激动剂同时又抑制中枢去甲肾上腺素再摄取,是迄今为止研发的第一个同时具有上述两种药理作用的单一分子药物。该药镇痛谱广,包括各种急性和慢性疼痛。对各种疼痛模型中包括神经病理性痛在内的多种大鼠疼痛模型有效,镇痛作用是吗啡的1/2～1/3。临床应用副反应轻微,耐受良好。
Hepattropine Hydrochloride is a novel dual-acting central analgesic that is both a mu-opioid receptor agonist and a central re-uptake of norepinephrine, and is the first of its kind to be developed to date with both The pharmacological effects of a single molecular drug. The drug has a broad spectrum of analgesics, including a variety of acute and chronic pain. A variety of pain models, including neuropathic pain, including a variety of rat pain model is effective, the analgesic effect is 1/2 ~ 1/3 of morphine. Side effects of clinical minor, well-tolerated.