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目的 :研究粗吻海龙水、醇提取液对成年雌性去势大鼠所致骨质疏松症的作用。方法 :将雌性成年大鼠切除卵巢 ,8周后测定有关指标 ,并与假手术组、模型组和尼尔雌醇组进行了比较。结果 :粗吻海龙水提取液灌胃组的骨灰重、骨钙含量、骨断裂力均明显高于模型组 (P <0 .0 5 )。结论 :提示粗吻海龙提取液对去势大鼠造成的骨质疏松症有一定的治疗作用。
Objective : To study the effects of crude seawater and alcohol extracts on osteoporosis induced by female ovariectomized rats. Methods : The female adult rats were ovariectomized. The relevant indexes were determined after 8 weeks and compared with the sham group, model group and nilestriol group. Results : The weight of bone ash, bone calcium content and fracture force of bone in the group fed with the crude oil of the rough-breasted sea dragon water were significantly higher than those in the model group (P<0.05). Conclusion : It is suggested that the crude extract of Haematopus japonicus has a certain therapeutic effect on osteoporosis caused by ovariectomized rats.