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目的观察低分子肝素联合辛伐他汀治疗不稳定型心绞痛的临床效果。方法选取我院2011年1月至2012年5月期间接受治疗的不稳定型心绞痛患者49例,并随机分为实验组和对照组,对照组实施常规治疗,实验组实施低分子肝素联合辛伐他汀治疗,观察两组在心电图、心绞痛痛的程度表现以及发作的次数表现、有效、无效的例数及比例,血脂变化等各项综合指数有无明显差异。结果 49例患者中,两组在临床症状、心电图、血脂变化、疗效等方面差异有统计学意义(P<0.05)。其中,实验组显效7例(28%),有效16例(65%),无效4例(7%),总有效率93%;对照组显效4例(15%),有效12例(61%)无效6例(24%),总有效率76%。观察组有效率明显高于对照组。结论低分子肝素联合辛伐他汀治疗不稳定型心绞痛具有良好的临床效果,值得推广应用。
Objective To observe the clinical effect of low molecular weight heparin combined with simvastatin in the treatment of unstable angina pectoris. Methods Forty-nine patients with unstable angina pectoris who were treated in our hospital from January 2011 to May 2012 were selected and randomly divided into experimental group and control group. The control group received routine treatment. The experimental group received low molecular weight heparin combined with simvastatin Statin treatment, the two groups in the ECG, angina pectoris and the performance of the frequency of attacks, the number of cases of effective and ineffective, the ratio of changes in blood lipids and other comprehensive index whether significant difference. Results Among the 49 patients, there were significant differences in clinical symptoms, electrocardiogram, blood lipids and curative effects between the two groups (P <0.05). Among them, 7 cases (28%) were effective in the experimental group, 16 cases (65%) were effective, 4 cases (7%) were ineffective, the total effective rate was 93% ) Ineffective in 6 cases (24%), the total effective rate of 76%. Observation group, the effective rate was significantly higher than the control group. Conclusion Low molecular weight heparin combined with simvastatin has a good clinical effect in the treatment of unstable angina pectoris, and it is worth popularizing and applying.