胰岛素治疗高血压脑出血高血糖反应对患者预后影响的临床研究

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目的探讨非糖尿病高血压脑出血后高血糖反应及胰岛素治疗对其预后的影响。方法按格拉斯哥昏迷计分(GCS) ,将 3~ 5分、6~ 8分、9~ 12分患者按极重型、重型、轻型 3大组分类。随机分成胰岛素治疗组与对照组 ,观察治疗 1个月。结果血糖水平与GCS、预后显著相关 (P <0 .0 1)。用胰岛素治疗能改善重型患者的预后 (P <0 .0 5 ) ,而在极重型及轻型组内预后比较无显著差异 (P >0 .0 5 )。结论测定血糖有助于了解脑出血的严重程度 ,估计患者预后。胰岛素能改善重型患者预后 ,而对极重型或轻型患者无明显差异。 Objective To investigate the effect of hyperglycemic response and insulin therapy on the prognosis of non-diabetic hypertensive intracerebral hemorrhage. Methods According to the Glasgow Coma Scale (GCS), 3 to 5, 6 to 8, and 9 to 12 patients were classified into 3 groups according to the categories of extremely heavy, heavy and light. Randomly divided into insulin treatment group and control group, observation and treatment of 1 month. Results The blood glucose level was significantly associated with GCS and prognosis (P <0.01). Insulin treatment can improve the prognosis of severe patients (P <0.05), while in the very severe and mild group, the prognosis was no significant difference (P> 0.05). Conclusion Determination of blood glucose helps to understand the severity of cerebral hemorrhage and estimate the prognosis of patients. Insulin can improve the prognosis of patients with severe, but no significant difference in very heavy or light patients.
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