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目的:在高原地区探讨阻塞性睡眠呼吸暂停低通气综合征(OSAHS)与2型糖尿病的关系。方法:分别检测OSAHS患者及正常人各50例的空腹血糖及餐后2h血糖、空腹胰岛素及餐后2h胰岛素。结果:OSAHS组空腹及餐后2h的血糖与胰岛素水平均显著高于对照组。结论:OSAHS可引起糖代谢异常,尤其是在高原地区,因为缺氧,诱发和促进2型糖尿病的发生、发展。OSAHS的治疗应作为对2型糖尿病患者的一项常规辅助治疗。
Objective: To investigate the relationship between obstructive sleep apnea-hypopnea syndrome (OSAHS) and type 2 diabetes mellitus in the plateau area. Methods: The fasting blood glucose and fasting blood glucose, fasting insulin and postprandial 2h insulin were measured in 50 patients with OSAHS and normal respectively. Results: The fasting and postprandial blood glucose and insulin levels of OSAHS group were significantly higher than those of control group. Conclusion: OSAHS can cause abnormal glucose metabolism, especially in the high altitude areas, because of hypoxia, induce and promote the development of type 2 diabetes. OSAHS treatment should be used as a routine adjuvant therapy for patients with type 2 diabetes.