卡托普利(captopril,巯甲丙脯酸)是目前常用的血管紧张素转换酶(ACE)抑制剂,在高血压、充血性心力衰竭中的应用日趋广泛。常见的不良反应有皮疹、味觉障碍、中性白细胞减少、蛋白尿、血管性水肿等,但引起咳嗽者不多,约占1.1％,今报道1例。患者女,45 yr,因心悸、胸闷20 d于1988年5月23日入院。1973年体检时发现“风湿性心脏病,二尖瓣狭窄”,1987年12月出现心房纤颤。1988年 Captopril (captopril), a commonly used angiotensin converting enzyme (ACE) inhibitor, is widely used in the treatment of hypertension and congestive heart failure. Common adverse reactions are rash, taste disorders, neutropenia, proteinuria, angioedema, but not many cough, accounting for about 1.1%, 1 case reported. Female patient, 45 yr, due to heart palpitations, chest tightness 20 d was admitted on May 23, 1988. 1973 physical examination found “rheumatic heart disease, mitral stenosis”, in December 1987 atrial fibrillation. 1988