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目的:运用循证医学,系统整理1949~1978年间国内发表的《伤寒论》大柴胡汤的临床防治性文献,分析文章概况(发表时间及发布期刊)并进行文献质量评估。方法:电子检索中国知网CNKI,全面收集1949~1978年《伤寒论》大柴胡汤方的相关文献,辅以手工检索。给予循证医学的原则和方法对文献进行分类统计。依据循证医学证据的等级标准和《<伤寒论>医学文献发表质量评分表》[1](简称《评分表》)分别对纳入的临床研究文献、个案经验文献进行评估。结果:纳入60篇,其中个案经验文献19篇(医案43则),临床研究文献41篇;个案文献均属于E级证据,仅一篇高质量文献,临床研究文献中C级证据1篇(采用了随机对照研究),D级证据40篇。结论:纳入文献数量较少,年代分布较为集中,高质量医案文献数量较集中。临床研究文献集中探讨了以中西医结合方法治疗急性溃疡病穿孔、胆系感染、急性胰腺炎三种急腹症疾病。
OBJECTIVE: To systematically summarize the clinical literatures about DCHB in Treatise on Febrile Diseases from 1949 to 1978 by means of evidence-based medicine and to analyze the general situation (time of publication and publication of journals) and evaluate the quality of the literature. Methods: CNKI was electronically searched, and a comprehensive collection of articles about DCHB Decoction from Treatise on Febrile Diseases from 1949 to 1978 was supplemented by manual search. To give evidence-based medicine principles and methods of classification of the literature statistics. According to the level of evidence of evidence-based medicine and “published on the Shanghan Lun> medical literature quality score sheet” [1] (referred to as the “score sheet”) were included in the clinical research literature, the case of empirical literature to assess. Results: Sixty articles were included, of which 19 cases were medical records (43 cases) and 41 articles were clinical studies. Each case file belongs to grade E evidence, only one high quality document and one C-grade evidence from clinical research literature Using a randomized controlled study), D-class evidence of 40 articles. Conclusion: The number of included literature is small, the distribution of age is more concentrated, and the number of high quality medical documents is more concentrated. Clinical research literature focused on the combination of traditional Chinese and Western medicine treatment of acute ulcer disease perforation, gallbladder infection, acute pancreatitis three acute abdomen disease.