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研究认为,黑色素瘤的发病率不断增加可能与环境中的危险因素相关,而从营养学和毒理学方面研究认为一些微量元素与该病发病有一定联系。在皮肤黑色素瘤的患者和对照人群的问卷调查和趾甲取样检测微量元素的研究中,利用电感耦合等离子体发射光谱法和中子活化分析法,检测趾甲中镉、铬、铅、硒、锌、铜以及铁的含量。研究结果显示,黑色素瘤患者体内铜含量较高,而铁的浓度较低,同时其他微量元素未观察到有明显差异。在病例与对照者之间锌和铜相关的形式与饮食中某些因素的估计摄入量具有差异。研究结果表明,铜和铁的异常摄入或者新陈代谢可能与黑色素瘤的病因有一定关系,而镉、铬、铅、硒和锌并未被证实参与黑色素瘤的发生。
Studies suggest that the increasing incidence of melanoma may be related to environmental risk factors, and from the nutritional and toxicological studies that some trace elements and the incidence of the disease have a certain connection. In the questionnaire of skin melanoma patients and control subjects and the study on the detection of trace elements in toenail samples, the content of cadmium, chromium, lead, selenium, zinc, zinc and cadmium in toenails were detected by inductively coupled plasma atomic emission spectrometry and neutron activation analysis. Copper and iron content. The results showed that patients with melanoma in vivo higher copper content, while the iron concentration is lower, while other trace elements were not observed were significantly different. There is a difference in the estimated intake of zinc and copper-related forms between the case and control subjects and certain factors in the diet. The results show that the abnormal intake of copper and iron or metabolism may have a certain relationship with the cause of melanoma, and cadmium, chromium, lead, selenium and zinc have not been confirmed to participate in the occurrence of melanoma.