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目的观察藻酸双酯钠治疗老年冠心病的疗效。方法58例患者分为藻酸双酯钠注射液治疗组(n=30)与硝酸甘油注射液对照组(n=28),观察两组治疗前后的心输出量(CO)、心脏指数(CI)、射血分数(EF)、ST段压低总次数、ST段压低总时间等参数及临床症状与综合评分。结果治疗组治疗后CO、CI和EF较治疗前均显著增加(P<0.01),而对照组上述参数无明显变化(P>0.05);治疗组治疗后ST段压低总次数、ST段压低总时间均较治疗前显著减少(P<0.01),而对照组未见明显变化;临床症状评分两组治疗后均有明显改善,但治疗组较对照组症状改善更为明显(P<0.01)。结论藻酸双酯钠注射液治疗老年冠心病疗效肯定,安全有效。
Objective To observe the effect of sodium alginate on elderly patients with coronary heart disease. Methods 58 patients were divided into sodium alginate injection group (n = 30) and nitroglycerin injection group (n = 28). The cardiac output (CO), cardiac index ), Ejection fraction (EF), total number of ST segment depression, total ST depression time and other parameters and clinical symptoms and comprehensive score. Results After treatment, the CO, CI and EF in the treatment group were significantly increased (P <0.01), while those in the control group showed no significant changes (P> 0.05). The total number of ST depression, ST depression (P <0.01), but there was no obvious change in the control group. The clinical symptom scores were significantly improved in both groups after treatment, but the symptom improvement in the treatment group was more obvious than that in the control group (P <0.01). Conclusion Sodium alginate injection in the treatment of elderly patients with coronary heart disease is effective, safe and effective.