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雌激素受体α和雌激素受体β分别是由ESR1和ESR2基因编码。不同个体间控制性超促排卵的临床结局有很大的差异,这会导致卵巢反应过低或严重的卵巢过度刺激征的发生。本文从雌激素受体基因多态性与控制性超促排卵结局的相关性作一综述。
Estrogen receptor alpha and estrogen receptor beta are, respectively, encoded by the ESR1 and ESR2 genes. The clinical outcome of controlled ovarian hyperstimulation among different individuals is very different, which can lead to ovarian response is too low or severe ovarian hyperstimulation occurs. This article reviews the association between estrogen receptor gene polymorphisms and controlled ovarian hyperstimulation (OVA) outcomes.