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目的探讨解脲支原体(UU)感染对妊娠结局的影响。方法选取2011年1月至2013年3月进入辽宁省沈阳市铁西区妇婴医院待产的孕妇311例,根据解脲支原体检测结果分为阳性组(135例)和阴性组(176例),比较两组孕妇妊娠结局及母婴产后患病情况。结果阳性组孕妇胎膜早破、早产、低出生体重儿发生率均明显高于阴性组,差异均有统计学意义(均P<0.05);阳性组的产褥感染、新生儿肺炎、新生儿黄疸发生率均明显高于阴性组,差异均有统计学意义(均P<0.05)。结论 UU感染阳性更易导致低体重儿、早产、胎膜早破、产褥感染、新生儿肺炎、新生儿黄疸发生,需重视及加强产前监测并系统治疗UU感染,以防不良妊娠结局发生。
Objective To investigate the influence of UU infection on pregnancy outcome. Methods A total of 311 pregnant women were enrolled in the Maternal and Child Hospital of Tiexi District in Shenyang City, Liaoning Province from January 2011 to March 2013. According to the results of Ureaplasma urealyticum test, 135 pregnant women and 176 negative pregnant women were enrolled. Pregnancy outcomes and maternal and child morbidity in both groups were compared. Results The positive rate of premature rupture of membranes, premature birth and low birth weight infants in the positive group were significantly higher than those in the negative group (all P <0.05). In the positive group, puerperal infection, neonatal pneumonia, neonatal Jaundice incidence were significantly higher than the negative group, the difference was statistically significant (P <0.05). Conclusion Positive UU infection can lead to low birth weight infants, premature rupture of membranes, puerperal infection, neonatal pneumonia and neonatal jaundice. Prenatal surveillance and prenatal monitoring should be emphasized and UU infection systematically treated to prevent adverse pregnancy outcome.