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活性氧族(ROS)通过对血管固有细胞功能的调节,在正常血管生理中发挥作用;而ROS的过度产生就会导致氧化应激,引起内皮功能障碍,促进心血管疾病的发生发展。内皮祖细胞(EPC)具有修复内皮及血管新生的作用,从而改善内皮功能,阻止心血管疾病的恶化,然而心血管疾病中大量表达的ROS能
Reactive oxygen species (ROS) play a role in normal vascular physiology through the regulation of the intrinsic cellular functions of blood vessels. Overproduction of ROS can lead to oxidative stress, cause endothelial dysfunction and promote the development of cardiovascular diseases. Endothelial progenitor cells (EPCs) have the role of repairing endothelial and angiogenesis, thereby improving endothelial function and preventing the worsening of cardiovascular diseases. However, ROS, which is abundantly expressed in cardiovascular diseases,