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目的 了解急性脑血管病患者血清白介素－ ８（ Ｉ Ｌ － ８） 改变的意义。方法 采用 Ｅ Ｌ Ｉ Ｓ Ａ 方法测定了３０ 例急性脑血管病患者（１６ 例脑出血，１４ 例 脑梗死） 和３０ 例健康 对照者的血清 Ｉ Ｌ － ８ 含量。结果 急性 脑血管病患者血清 Ｉ Ｌ － ８ 水 平（９７５４ ±３０８１ ｎｇ／ Ｌ） 明显高于正常对照组（５１３５ ±１３２９ ｎｇ／ Ｌ） 。急性脑出血和急性脑梗死组患者血清 Ｉ Ｌ － ８ 水平（１０５２８ ±１８９１ ｎｇ／ Ｌ 和９４８９ ±３２１４ ｎｇ／ Ｌ） 均明显高于正常对照组，而它们之间则无明显差别。结论 急性脑血管病患者 急性期血清 Ｉ Ｌ － ８ 水平 明显升高，提示 Ｉ Ｌ － ８ 可能参与了急性脑血管病的发病过程。
Objective To understand the significance of serum interleukin - 8 (IL - 8) in patients with acute cerebrovascular disease. Methods Serum IL - 8 levels were measured in 30 patients with acute cerebrovascular disease (16 with cerebral hemorrhage and 14 with cerebral infarction) and 30 healthy controls by ELISA method. Results The level of serum IL - 8 in patients with acute cerebrovascular disease (9754 ± 3081 ng / L) was significantly higher than that of the control group (5135 ± 1329 ng / L). The levels of serum IL-8 in patients with acute cerebral hemorrhage and acute cerebral infarction were significantly higher than those in the normal control (10528 ± 1891 ng / L and 9489 ± 3214 ng / L) There is no significant difference. Conclusion The level of serum IL - 8 in patients with acute cerebrovascular disease is significantly increased in acute phase, suggesting that IL - 8 may be involved in the pathogenesis of acute cerebrovascular disease.