随着分子生物学技术的发展,近年来对肺癌的认识已经从较宏观的细胞学、组织学深入到更加微观的遗传学与分子生物学领域。研究发现,癌基因、抑癌基因及生长因子家族及其受体的异常表达或突变在肺癌的发生、发展中有重要作用,并在肿瘤血管形成、浸润与转移分子机制的研究方面有了一定突 With the development of molecular biology techniques, the awareness of lung cancer in recent years has gone deeper from the macroscopical cytology and histology to the more micro-genetics and molecular biology. The study found that abnormal expression or mutation of oncogenes, tumor suppressor genes and growth factor families and their receptors plays an important role in the occurrence and development of lung cancer and has certain significance in the study of the molecular mechanisms of tumor angiogenesis, invasion and metastasis sudden