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目的探讨益气化瘀汤联合氯吡格雷及阿司匹林治疗急性心肌梗死(AMI)的临床疗效。方法选取2014年5月—2015年4月贵州省遵义县人民医院收治的AMI患者72例,采取随机双盲法分为研究组与对照组,各36例。对照组患者予以阿司匹林联合氯吡格雷治疗,研究组患者在对照组基础上加用益气化瘀汤治疗。观察两组患者临床疗效、生活质量评分、胸痛复发、再闭塞及再发心肌梗死的情况。结果研究组患者总有效率高于对照组,躯体功能、心理功能、社会功能、物质生活评分高于对照组,胸痛复发、再闭塞及再发心肌梗死率低于对照组,差异有统计学意义(P<0.05)。结论益气化瘀汤联合氯吡格雷及阿司匹林治疗AMI的临床疗效显著,可提高患者的生活质量,降低疾病复发率。
Objective To investigate the clinical efficacy of Yiqi Huayu Decoction combined with clopidogrel and aspirin in the treatment of acute myocardial infarction (AMI). Methods 72 patients with AMI admitted to Zunyi County People’s Hospital of Guizhou Province from May 2014 to April 2015 were randomly divided into study group and control group with 36 cases in each group. Patients in the control group were treated with aspirin combined with clopidogrel. Patients in the study group were treated with Yiqi Huayu Decoction on the basis of the control group. The clinical efficacy, quality of life score, chest pain recurrence, reocclusion and recurrent myocardial infarction were observed in two groups. Results The total effective rate of study group was higher than that of control group. Body function, psychological function, social function and physical life score were higher than those of control group. The recurrence of chest pain, reocclusion and recurrent myocardial infarction rate were lower than those of control group (P <0.05). Conclusion Yiqi Huayu Decoction combined with clopidogrel and aspirin in the treatment of AMI has significant clinical efficacy, which can improve the quality of life of patients and reduce the recurrence rate.