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1型糖尿病是遗传学上易感个体胰岛 β细胞自身免疫性损害引起的疾病。作为 1型糖尿病的免疫标志 ,胰岛细胞抗体 (ＩＣＡ)和谷氨酸脱羧酶抗体 (ＧＡＤＡ)受到广泛重视。80 %左右新发现的 1型糖尿病患者 (病程 1年 )ＩＣＡ阳性 ,但数年后大多数患者ＩＣＡ转阴 ,原因在于胰岛 β?
Type 1 diabetes is a disease caused by autoimmune damage of islet beta cells in genetically predisposed individuals. As an immune marker of type 1 diabetes, islet cell antibodies (ICA) and glutamic acid decarboxylase antibodies (GADA) are widely recognized. ICA is positive in about 80% of newly diagnosed Type 1 diabetic patients (one year duration), but ICA is negative in most patients after a few years due to islet beta?