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目的:探讨黄芪对高原人体运动能力的作用。方法:选择40名已习服3 700m高原半年以上的男青年,随机分为黄芪组(n=20,黄芪4.4克/日,连续服药15天)和对照组(n=20,服用安慰剂15天)。按照军标GJB1337-92测定服药前、后体能指标,采静脉血检测谷氨酰氨基转移酶(GPT)、天冬氨酸氨基转移酶(GOT)、总胆红素(TB)、直接胆红素(DB)、血乳酸(BLA)、尿素氮(BUN)、丙二醛(MDA)、超氧化物歧化酶(SOD)、一氧化氮(NO)及一氧化氮合酶(NOS)的含量。结果:对照组运动后GPT、GOT、TB、DB、MDA、BUN、BLA等指标较运动前均显著增高,SOD、NO、NOS显著降低(P<0.05或P<0.01);与服药前相比,黄芪组VO2max、PWC170、台阶指数均显著增高,运动后SOD、NO、NOS较运动前显著增高,GPT、GOT、TB、DB、MDA、BUN、BLA均显著降低(P<0.05或0.01)。结论:黄芪具有抗疲劳、提高高原人体运动能力的作用,减轻低氧对环境肝脏的损害。
Objective: To investigate the effect of astragalus on the movement ability of human in high altitude. Methods: Forty young men who had served more than 6 months at 3 700 m plateau were randomly divided into three groups: astragalus membranaceus (n = 20, Astragalus 4.4 g / d, continuous administration for 15 days) and control group (n = 20) day). According to the military standard GJB1337-92, the physical indexes of the patients before and after taking the medicine were measured, and the venous blood was collected to detect the levels of GPT, GOT, TB, The content of blood urea nitrogen (BLA), blood urea nitrogen (BUN), malondialdehyde (MDA), superoxide dismutase (SOD), nitric oxide (NO) and nitric oxide synthase (NOS) . Results: Compared with those before exercise, the indexes of GPT, GOT, TB, DB, MDA, BUN and BLA in the control group were significantly increased (P <0.05 or P <0.01) (P <0.05 or 0.01). The levels of VO2max, PWC170 and step index in astragalus group were significantly higher than those before exercise. The activities of SOD, NO and NOS in astragalus group were significantly higher than those before exercise, and GPT, GOT, TB, DB, MDA, BUN, Conclusion: Astragalus has the effect of resisting fatigue, improving the movement ability of the human body at high altitude and reducing the damage to the environment liver caused by hypoxia.