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目的总结动脉导管未闭(PDA)介入封堵治疗的临床疗效和随访结果。方法 PDA患者35例,男14例,女21例,年龄3～55岁,体重10～62 kg,肺动脉高压26例,肺动脉平均压33～61 mm Hg(1 mm Hg=0.133 kPa),19例患者左心室扩大。降主动脉侧位造影显示病理解剖类型为漏斗型29例,管型6例,最窄处直径2～10 mm,均经股静脉途径行封堵术,超声心动图随访。结果所有患者均成功封堵,术后即刻完全封堵33例,2例有少量残余分流,术后24 h彩色多普勒超声检查示分流消失,随访6～96个月,肺动脉压均有下降,左心室内径较前缩小,无严重并发症。结论 PDA介入封堵治疗是安全有效的方法。
Objective To summarize the clinical efficacy and follow-up results of patent ductus arteriosus closure (PDA). Methods A total of 35 PDA patients, including 14 males and 21 females, aged 3 to 55 years, weighing 10 to 62 kg, pulmonary hypertension 26 and pulmonary hypertension 33 to 61 mm Hg (1 mm Hg 0.133 kPa), 19 Patients with left ventricular enlargement. Side of the descending aorta angiography showed pathological anatomy types of funnel in 29 cases, 6 cases of tube, the narrowest diameter of 2 ~ 10 mm, were blocked by the femoral vein approach, echocardiography follow-up. Results All the patients were successfully occluded. Immediately after the operation, 33 cases were completely blocked and 2 cases had a small residual shunt. Color Doppler echocardiography showed that the shunt disappeared 24 h after operation. Pulmonary arterial pressure decreased after 6 to 96 months of follow-up , Left ventricular diameter smaller than before, no serious complications. Conclusion PDA intervention is a safe and effective method.