盘状红斑狼疮 (ＤＬＥ)是一种累及皮肤或口腔黏膜的结缔组织疾病 ,病因迄今未完全明确。临床上不同部位、不同时期表现复杂多样 ,常与扁平苔藓、唇炎及白斑类疾病相混淆。现将经过临床、组织病理及结合免疫病理确诊的 5 3例ＤＬＥ患者 ,着重对其组织病理特征 ,以及鉴别诊断进行 Discoid lupus erythematosus (DLE) is a connective tissue disease involving the skin or oral mucosa, the etiology of which has not yet been fully understood. Clinically different parts of different periods of complex and diverse performance, often with lichen planus, cheilitis and white spot disease confused. Now through clinical, histopathological and immunopathological diagnosis of 53 cases of DLE patients, focusing on their histopathological features, as well as differential diagnosis