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目的探讨亚低温治疗新生儿缺血缺氧性脑病的临床疗效及临床应用的可行性。方法回顾性分析92例经CT或MRI检查确诊的缺血缺氧性脑病(HIE)新生儿临床资料,所有患儿均在常规治疗基础上加用亚低温治疗,观察患儿治疗后的临床疗效及神经系统症状,对安全性进行评价。结果本组92例HIE患儿在常规治疗基础上采用亚低温治疗后,有效率89.2%,治疗后患儿神经系统症状发生率为5.4%。结论亚低温治疗新生儿缺氧缺血性脑病是安全可行的,能够取得较好的临床治疗效果,值得临床进一步推广使用。
Objective To investigate the clinical effect of mild hypothermia on neonatal hypoxic-ischemic encephalopathy and its feasibility of clinical application. Methods The clinical data of 92 neonates with hypoxic-ischemic encephalopathy (HIE) diagnosed by CT or MRI were retrospectively analyzed. All children were treated with mild hypothermia on the basis of routine treatment, and the clinical effect of treatment was observed And neurological symptoms, evaluate the safety. Results 92 cases of HIE children on the basis of routine treatment with mild hypothermia, the effective rate was 89.2%, the incidence of neurological symptoms in children after treatment was 5.4%. Conclusion Mild hypothermia treatment of neonatal hypoxic-ischemic encephalopathy is safe and feasible, to obtain better clinical treatment, it is worth further promotion of clinical use.