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目的:探讨心肌损伤生化标志物(cTnI、CK-MB、CRP、DD、UA)在急性缺血性胸痛诊断中的临床意义。方法:比较2010年11月-2012年12月收治的急性心肌梗死组(A组,n=80)、心绞痛组(B组,n=80)和正常对照组(C组,n=80)患者血清cTnI、CK-MB、DD、CRP、UA的含量。结果:A组的cTnI、CK-MB、CRP检测阳性率均明显高于B组和C组(P均<0.05),A组的DD、UA检测阳性率也明显高于C组(P均<0.05)。结论:cTnI、CK-MB、CRP、DD、UA各自的特点不同,联合检测心肌损伤生化标志物在急性胸痛诊断中具有重要的临床意义。
Objective: To investigate the clinical significance of myocardial biochemical markers (cTnI, CK-MB, CRP, DD, UA) in the diagnosis of acute ischemic chest pain. METHODS: Patients in the AMI group (n = 80), angina pectoris group (n = 80), and control group (n = 80) were compared between November 2010 and December 2012 Serum cTnI, CK-MB, DD, CRP, UA content. Results: The positive rates of cTnI, CK-MB and CRP in group A were significantly higher than those in group B and C (all P <0.05). The positive rates of DD and UA in group A were significantly higher than those in group C (all P < 0.05). Conclusion: The characteristics of cTnI, CK-MB, CRP, DD and UA are different. The combined detection of biochemical markers of myocardial injury has an important clinical significance in the diagnosis of acute chest pain.