目的探讨瞬态诱发耳声发射(transientevokedotoacousticemission,TEOAE)应用于新生儿窒息听力筛查的可行性及临床意义。方法对重症监护室住院的164例窒息新生儿及60例健康新生儿应用CELESTA503耳声发射仪进行TEOAE检测,出院前和3个月后复查。结果第一次窒息新生儿TEOAE通过率为6274%,健康新生儿TEOAE通过率为95%,两组检出率经统计学分析,差异有非常显著意义(P<001)。第二次窒息新生儿TEOAE通过率为8963%,第三次窒息新生儿TEOAE通过率为9412%。结论TEOAE是快速可行的高危新生儿听力筛查方法;新生儿测试TEOAE的通过率与窒息程度有关;窒息对耳蜗功能的影响是可逆的。 Objective To investigate the feasibility and clinical significance of transient evoked otoacoustic emission (TEOAE) in hearing screening of neonatal asphyxia. Methods Totally 164 neonates with asphyxia and 60 healthy newborns hospitalized in intensive care unit were examined by TEELE with CELESTA503 otoacoustic emission apparatus and were reviewed before discharge and 3 months after discharge. Results The first passage of asphyxia neonatal TEOAE was 6274%, the healthy neonatal TEOAE passage rate was 95%, the two groups were statistically significant, the difference was significant (P <001). The second passage of asphyxia neonatal TEOAE was 8963%, the third passage of neonatal TEOAE as 9412%. CONCLUSION: TEOAE is a fast and feasible method for high-risk neonatal hearing screening. The passing rate of neonatal test TEOAE is related to the degree of asphyxia. The effect of asphyxia on cochlear function is reversible.