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目的:观察复方奥硝唑大黄口腔膜对Wistar大鼠实验性口腔溃疡的治疗作用。方法:建立Wistar大鼠口腔溃疡动物模型,将模型动物随机分成5组:复方奥硝唑大黄口腔膜高、中、低剂量组、奥硝唑膜阳性对照组和模型对照组,观察给药后溃疡面的愈合情况。结果:各剂量复方奥硝唑大黄口腔膜均能不同程度减小溃疡面直径。结论:复方奥硝唑大黄口腔膜对Wistar大鼠实验性口腔溃疡有较好的治疗作用。
Objective: To observe the therapeutic effect of compound ornidazole rhubarb oral membrane on experimental oral ulcer in Wistar rats. Methods: Animal model of oral ulcer in Wistar rats was established. The model animals were randomly divided into 5 groups: compound ornidazole rhubarb oral cavity high, medium and low dose group, ornidazole membrane positive control group and model control group. Ulcer healing. Results: The ornidazole and rhubarb oral mucosa at different doses all reduced the ulcer surface diameter to some extent. Conclusion: The compound ornidazole rhubarb oral membrane has a good therapeutic effect on experimental oral ulcer in Wistar rats.