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Polyvinyl alcohol (PVA) hydrogel (15%w/w) was processed by freezing and thawing from one through six thermal cycles to obtain wide range of mechanical properties. The materials were tested under uniaxial tension and results show that matching mechanical properties to that of porcine aortic root can be achieved. A fatigue machine for elastomer materials and tissues was built and fatigue test on PVA sample was carried out. The test results show that the PVA has good fatigue property. The stent prototype was designed and successfully made by mold casting method. Some potential medical applications are discussed.