目的:探究全程护理干预对利培酮治疗精神分裂症患者不良反应的影响。方法:选取我院自2015年9月~2017年2月精神科收治的精神分裂症患者65例,按数字奇偶法分为观察组和对照组,对照组30例实施精神科常规护理;观察组35例据利培酮产生的不良反应行全程护理干预。比较护理过程中,两组患者的不良反应发生率。结果:观察组震颤、便秘、嗜睡等不常见不良反应的发生率明显低于对照组,但差异无统计学意义(P>0.05);焦虑、心率过速、头昏头痛、静坐不能和肌强直等常见不良反应的发生率比较,观察组明显低于对照组(P<0.05),差异具有统计学意义。结论:相比常规护理,全程护理干预的实施更有助于降低利培酮治疗精神分裂症患者不良反应的发生率,以促使患者更好地配合临床治疗,改善生活质量。 Objective: To investigate the effect of full nursing intervention on adverse reactions of risperidone in patients with schizophrenia. Methods: Sixty-five schizophrenics admitted in our hospital from September 2015 to February 2017 were divided into observation group and control group according to digital parity method. Thirty patients in control group were enrolled in routine psychiatric nursing. Observation group According to the adverse reactions of risperidone, 35 patients received full-time nursing intervention. In the nursing process, two groups of patients with adverse reactions incidence. Results: The incidence of unusual adverse reactions such as tremor, constipation and drowsiness in observation group was significantly lower than that in control group (P> 0.05); anxiety, tachycardia, dizziness, headache, The incidence of common adverse reactions such as the observation group was significantly lower than the control group (P <0.05), the difference was statistically significant. CONCLUSIONS: Compared with routine nursing care, the implementation of full-time nursing intervention is more helpful to reduce the incidence of adverse reactions of risperidone in patients with schizophrenia so as to promote patients to better cooperate with clinical treatment and improve the quality of life.