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莫诺苯宗(氢醌单等醚,monobenzone)是一种祛斑药,比氢醌性质稳定,刺激性小,作用强,美国药典XXⅡ版已收载[1],我国尚未生产。莫诺苯宗祛除色斑的主要机理是抑制邻苯二酚氧化酶,阻止多巴氧化成多巴酿进而形成黑色素[2]。称取氢酿4.8g,加入苯甲醇20g,搅拌溶解,在120℃
Monobenzone (hydroquinone ethers, monobenzone) is a freckle drug, which is stable, less irritating and more potent than hydroquinone. The United States Pharmacopoeia XXII has been included [1] and has not been produced yet in our country. Monobenzide eliminate the main mechanism of stain is inhibition of catechol oxidase, prevent dopa oxidation into dopa brewing and the formation of melanin [2]. Weigh 4.8g of hydrogen brewing, add benzyl alcohol 20g, stirring to dissolve at 120 ℃