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中医药发展的根本在于临床疗效,而临床疗效是否显著与药物的生物利用度紧密相关。中药(复方)物质基础的本质是多组分,就组分本身的性质而言,其生物利用度的高低很大程度上取决于组分的生物药剂学性质即溶解性和渗透性。因此,该文将在中医药理论指导下,结合中药现代制剂技术,从物质基础组分的层次阐明改善组分生物药剂学性质关键技术,以期提高中药组分制剂的临床疗效。
The development of traditional Chinese medicine is the fundamental clinical efficacy, and clinical efficacy is significantly related to the bioavailability of the drug. The essence of the material basis of traditional Chinese medicine (compound) is multi-component. The bioavailability depends largely on the biopharmaceutical properties of the components, ie solubility and permeability, in terms of the nature of the component itself. Therefore, under the guidance of traditional Chinese medicine theory, combined with the modern preparation technology of traditional Chinese medicine, the article will clarify the key technologies of improving the biopharmaceutical properties of the components from the perspective of the material basic components in order to improve the clinical efficacy of the traditional Chinese medicine component preparations.