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许多因素能够诱导细胞凋亡，如电离辐射、紫外线、低氧、缺血、中毒及化疗药物等；利用某种药物增加肿瘤细胞凋亡和减少正常细胞凋亡对于肿瘤防治具有重要意义。近年来，对癌症放化疗中正常组织保护的研究主要集中在氨基硫醇类和非硫醇类药物的作用研究，如氨基硫醇类WR－２７
Many factors can induce apoptosis, such as ionizing radiation, ultraviolet ray, hypoxia, ischemia, poisoning and chemotherapeutic drugs. Using certain drugs to increase tumor cell apoptosis and reduce normal cell apoptosis is of great significance for tumor prevention and treatment. In recent years, studies on the protection of normal tissues in radiotherapy and chemotherapy of cancer have mainly focused on the action of aminothiols and non-thiols such as aminothiols WR-27