冻伤是在一定条件下由寒冷引起的组织损伤。以组织坏死、脱落为结局的Ⅲ度和Ⅳ度冻伤,又称为重度冻伤。对于重度冻伤的治疗和发病机理的研究,除依靠临床经验积累外,主要是通过实验研究,为此,建立一个比较稳定而重复性好的模型是必要的。以往在重度冻伤实验研究中多采用定时定温的液体浸冻模型,但是这种模型往往个体差异较大。 Frostbite is a tissue injury caused by cold under certain conditions. Tissue necrosis, shedding as the outcome of Ⅲ degree and Ⅳ degree frostbite, also known as severe frostbite. For the treatment of severe frostbite and the pathogenesis of the study, in addition to relying on clinical experience, mainly through experimental research, to establish a more stable and repeatable model is necessary. In the past in the experimental study of severe frostbite more time-fixed liquid immersion model, but this model often individual differences.