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目的:研究新生儿缺氧缺血性脑病(HIE)的脑血流动力学的动态改变。方法:应用经颅多普勒(TCD)对89例HIE患儿及55例健康新生儿进行动态检查,并结合临床进行分析。结果:健康新生儿的大脑中动脉/颈内动脉流速比值(M/I)在0.9～1.2之间,轻度HIE的M/I在1.2～l.5之间;中重度HIE的M/I一般在1.8以上,其中M/I超过3.6以上者多死亡。结论:M/I与HIE临床有密切相关性,是HIE分度及预后估计的重要指标。
Objective: To study the dynamic changes of cerebral hemodynamics in neonates with hypoxic-ischemic encephalopathy (HIE). Methods: TCD was performed in 89 children with HIE and 55 healthy newborns. The clinical data were analyzed in combination with clinical data. Results: The ratio of M / I of middle cerebral artery / internal carotid artery in healthy newborns was between 0.9 and 1.2, M / I of mild HIE was between 1.2 and 1.5. M / I of moderate and severe HIE Generally more than 1.8, of which M / I more than 3.6 more deaths. Conclusion: M / I is closely related to HIE clinical and is an important index for HIE indexing and prognosis estimation.