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借助RIA,对28例胆囊结石男性(平均57.5岁)及26名健康中、老年男性(平均63.3岁)进行了血清雌二醇(E_2)、孕酮、睾酮和前列腺素类(PGs)检测,以探索胆石形成机理。结果,1)在胆石男病人中.平均E_2和平均孕酮水平均高,他们的平均睾酮则低下,与健康对照男性相应诸值比较,差异非常显著或显著(P<0.001,0.05,0.05);2)至于平均PGs,胆石男性组者与健康对照男性相比,前者也相当高(23.01pg/ml对16.31pg/ml),只是两组间差异尚无统计学意义。作者等初步设想,胆石男性小,如同胆石女性那般,本症也可能是某种垂体性腺激素分泌紊乱性疾病。
Serum estradiol (E2), progesterone, testosterone and prostaglandins (PGs) were measured in 28 males (average 57.5 years) and 26 healthy middle-aged and older males (average 63.3 years) with RIA. To explore the gallstone formation mechanism. Results: 1) The average E_2 and average progesterone levels in male patients with gallstone were high, and their mean testosterone levels were lower than those in healthy controls (P <0.001, 0.05, 0.05) ; 2) For the mean PGs, the former was also significantly higher in the gallstone men than in the healthy controls (23.01 pg / ml versus 16.31 pg / ml), although there was no statistical difference between the two groups. The initial idea of the author, gallstone men are small, as gallstone women, the disease may also be a kind of pituitary gonadal hormone secretion disorders.