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[目的]探讨贫血对晚期非小细胞肺癌(NSCLC)患者预后的影响。[方法]回顾性分析91例晚期NSCLC患者初诊时血红蛋白(HGB)水平,比较贫血组和非贫血组生存期的差异,分析NSCLC患者的预后影响因素。[结果]非贫血组的中位生存期较贫血组长,有统计学差异(14.7个月vs 10.4个月,P<0.05)。经Cox多因素分析发现,贫血、临床分期Ⅳ期是预后不良的独立危险因素。[结论]贫血缩短NSCLC患者的生存期,是影响预后的独立因素。
[Objective] To investigate the influence of anemia on the prognosis of patients with advanced non-small cell lung cancer (NSCLC). [Methods] The hemoglobin (HGB) level of 91 patients with advanced NSCLC was retrospectively analyzed. The difference of survival time between anemia patients and non-anemia patients was compared. The prognostic factors of NSCLC patients were analyzed. [Results] The median survival time of non-anemia patients was longer than that of anemia patients (14.7 months vs. 10.4 months, P <0.05). Cox multivariate analysis found that anemia, clinical stage Ⅳ is an independent risk factor for poor prognosis. [Conclusion] Anemia shortens the survival of patients with NSCLC, is an independent factor affecting the prognosis.