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目的对结节性硬化症的临床诊断及治疗进行探讨分析。方法将我院进行治疗的42例TSC患儿,随机将其分为两组,观察组21例给予单药治疗,对照组21例给予多药治疗。将治疗结果进行对比。结果对于两组患者随访半年至3年并对治疗效果进行观察记录,观察组有效率为80.95%,对照组有效率为52.38%,两组相比较差异具有统计学意义。结论 TSC的临床表现具有年龄特征,随着患儿年龄的成长,建议定期对脑、心脏、肝肾等器官进行复查及辅助检查,关注皮肤是否出现病变。对伴有癫痫发作的TSC患儿,应积极进行药物抗癫痫治疗。
Objective To study the clinical diagnosis and treatment of tuberous sclerosis. Methods Forty-two children with TSC who were treated in our hospital were randomly divided into two groups. In the observation group, 21 patients were given monotherapy and 21 patients in the control group were given multi-drug therapy. The treatment results were compared. Results The two groups of patients were followed up for six months to three years and the treatment effect was observed and recorded, the observation group was 80.95% effective rate was 52.38% in the control group, the difference between the two groups was statistically significant. Conclusion The clinical manifestations of TSC have the characteristics of age. With the growth of children’s age, it is recommended to regularly review and assist the examination of the brain, heart, liver and kidney and other organs, and pay attention to whether the lesions appear on the skin. For children with TSC associated with seizures, anti-epileptic drugs should be actively pursued.