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目的:评价乌司他丁对胰腺炎的临床疗效。方法:68例胰腺炎患者随机分为两组,治疗组30例(急性23例,慢性7例),对照组38例(急性29例,慢性9例)。对照组采用常规治疗。治疗组在常规治疗的基础上加用乌司他丁20万u/d静脉滴注,持续10d。结果:急性胰腺炎患者应用乌司他丁后,症状、体征的缓解及血尿淀粉酶的恢复明显早于对照组,总有效率优于对照组(P<0.05);慢性胰腺炎患者治疗组也优于对照组,但无统计学意义(P>0.05)。结论:乌司他丁对急性胰腺炎有较好疗效,可作为急性胰腺炎的有效治疗措施之一,对慢性胰腺炎的疗效有待进一步研究。
Objective: To evaluate the clinical effect of ulinastatin on pancreatitis. Methods: Sixty-eight patients with pancreatitis were randomly divided into two groups. The treatment group consisted of 30 patients (23 acute and 7 chronic) and 38 patients (29 acute and 9 chronic). Control group using conventional treatment. The treatment group was treated with ulinastatin 200 000 u / d intravenously on the basis of routine treatment for 10 days. Results: After ulinastatin was administered to patients with acute pancreatitis, the relief of symptoms and signs and the recovery of hematuria and amylase were significantly earlier than those in the control group, and the total effective rate was better than that of the control group (P <0.05). The treatment group with chronic pancreatitis Better than the control group, but not statistically significant (P> 0.05). Conclusion: Ulinastatin has a good curative effect on acute pancreatitis and can be used as an effective treatment for acute pancreatitis. The curative effect of chronic ulcer remains to be further studied.