论文部分内容阅读
心肺复苏(CPR)是指针对心脏骤停和心源性猝死的紧急抢救措施。完整的CPR包括基础CPR、高级CPR、心脏骤停后治疗、特殊情况复苏。该文主要涉及后期的心脏骤停后治疗。心脏骤停时,全身的血供和氧供暂停,组织和细胞会发生一系列缺血缺氧表现,及时给予CPR救治后,机体会出现缺血再灌注损伤等相关表现。CPR后的患者机体内出现大量活性氧等自由基等物质,活性氧可以激活全身性炎症反应(SIRS)。作者主要研究药物从SIRS角度来治疗CPR后的患者。主要介绍糖皮质激素、多巴胺、新活素及乌司他丁对CPR后患者的作用机制。
Cardiopulmonary resuscitation (CPR) is an emergency treatment for sudden cardiac arrest and sudden cardiac death. The complete CPR includes basic CPR, advanced CPR, post-cardiac arrest treatment, and special case recovery. This article mainly deals with post-cardiac arrest treatment. Cardiac arrest, the whole body of blood supply and oxygen for the suspension, tissue and cells will occur a series of hypoxia and hypoxia performance, timely CPR treatment, the body will appear ischemia-reperfusion injury and other related performance. After CPR, a large number of free radicals and other substances appeared in the body of patients, and reactive oxygen species can activate systemic inflammatory response (SIRS). The authors mainly studied patients after treatment of CPR from the SIRS perspective. The main introduction of glucocorticoid, dopamine, new activin and ulinastatin in patients with CPR mechanism.