标题化合物是合成ROR抑制剂、钠-葡萄糖共转运蛋白2抑制剂和5-HT2C兴奋剂的重要中间体。以对溴苯甲醛为起始原料,经Suzuki偶联、还原和溴代反应制得目标产物。本方法成本较低、操作简单且反应条件较为温和,总收率达62.8%。目标化合物的结构经1HNMR和MS确证。 The title compounds are important intermediates for the synthesis of ROR inhibitors, sodium-glucose cotransporter 2 inhibitors and 5-HT2C stimulants. Using p-bromobenzaldehyde as the starting material, the target product was obtained by Suzuki coupling, reduction and bromination reaction. The method has low cost, simple operation and mild reaction conditions, and the total yield is up to 62.8%. The structure of the target compound was confirmed by 1H NMR and MS.