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为比较单剂量阿齐红霉素(azithromycin)2.0g口服与单剂量头孢三嗪250mg肌注治疗无合并症淋病的疗效及耐受性,在美国十个市立性传播疾病诊所进行了多中心、开放、随机、对照试验。受试者为1991年与1992年就诊的男、女无合并症的淋病患者。参加研究的男性患者尿道涂片革兰染色均见多形核白细胞内含有革兰阴性双球菌;女性患者未经治疗且培养证明患有淋病;宫颈内或尿道涂片见含革兰阴性双球菌的多形核白细胞;或最近与患尿道淋病
To compare the efficacy and tolerability of a single dose of azithromycin 2.0g oral and single-dose ceftriaxone 250mg intramuscularly in the treatment of non-comorbid gonorrhea, ten centers of STD clinics in the United States were performed. Open, randomized, controlled trial. The subjects were male and female gonorrhea patients without complications in 1991 and 1992. Men who participated in the study had urethral smear Gram staining of polymorphonuclear leukocytes containing Gram-negative diphtheria; female patients untreated and cultured with gonorrhea; cervical or urethral smear see Gram-negative bacteria Polymorphonuclear leukocytes; or recently with urinary tract gonorrhea