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自1970年以来,人们对开发用生物可降解材料制备载药微囊的研究与日俱增。这种微囊注入体内,囊内药物可缓慢释放,囊壁材料(下称囊材)经酶解或非酶作用成为无毒产物,缓慢地经正常生理代谢途径排出体外。所以,它有比口服缓释剂型长得多的释药时间,又无需像植入剂型(implant)那样在用药前后用手术途径埋植或移除。这些优点一直受
Since 1970, there has been increasing research into the development of drug-loaded microcapsules using biodegradable materials. This microcapsule injected into the body, the drug can be slowly released within the capsule, wall material (hereinafter referred to as the capsule material) enzymatic or non-enzymatic action into a non-toxic products, slowly through the normal physiological metabolic pathways excreted. Therefore, it has a much longer release time than the oral sustained-release formulation and does not need to be surgically implanted or removed before and after the administration as an implant. These advantages have always been