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目的分析2013年广州市萝岗区一起在持续高蚊媒密度环境中但没有扩散的登革热疫情的流行病学特征,为制定预防控制措施提供科学依据。方法运用流行病学调查和病例主动搜索进行疫情分析,在疫情发生的第1、3、7、16、25d采用布雷图指数、容器指数、房屋指数和人工诱蚊法进行蚊媒密度调查,采用免疫荧光法进行病例和疫点人群血清标本登革热抗体Ig M和Ig G的检测。结果某患者为实验室诊断病例,无外出史,未搜索到疑似病例,无续发病例。疫情发生第1、3、7、16、25d,某患者工作单位疫点布雷图指数分别为50.0、25.0、12.5、3.1、3.1,宿舍疫点为26.7、10.8、6.8、4.4、0.0。疫情发生第d天,调查宿舍和单位共60名疫点人员中,1名血清标本登革热抗体Ig M阳性,为某患者工作单位员工。结论该起疫情是一起在持续高蚊媒密度环境中但没有扩散的登革热疫情,可能与病例工作地点人口密度低、单位员工不在白纹伊蚊的叮咬高峰期停留、疫点白纹伊蚊登革热病毒携带率低有关。
OBJECTIVE: To analyze the epidemiological characteristics of dengue fever in Luogang District of Guangzhou City in 2013 with no continuous spread in high mosquito density environment and provide a scientific basis for the development of prevention and control measures. Methods Epidemiological investigation and active case searching were used to analyze the epidemic situation. The density of mosquito was measured by Bretti Index, Container Index, Housing Index and artificial mosquito method on the 1st, 3rd, 16th, Immunofluorescence method was used to detect IgM and Ig G of dengue antibodies in serum samples of cases and outbreaks. Results of a case of laboratory diagnosis of patients, no history of the outside, did not search for suspected cases, no cases of recurrence. The first, the third, the seventh, the twentieth and the seventy-five days after the onset of the outbreak, the Brettones index of the working unit was 50.0, 25.0, 12.5, 3.1, and 3.1 for the patient and 26.7, 10.8, 6.8, 4.4 and 0.0. On day d of the outbreak, a total of 60 outbreaks were investigated among dormitories and units. One of the serum samples was positive for dengue antibody Ig M, and was a working unit employee of a patient. Conclusions The outbreak was an outbreak of Dengue Fever together in a continuous high mosquito-density environment but without spreading. It is possible that the work place population density is low and that unit employees do not stay at the bite peak of Aedes albopictus. The outbreak of Aedes albopictus dengue Low viral load.